[HTML][HTML] Does the presence of multiple β-lactamases in Gram-negative bacilli impact the results of antimicrobial susceptibility tests and extended-spectrum β …

FC Tenover, CM dela Cruz, S Dewell, VM Le… - Journal of Global …, 2020 - Elsevier
Abstract Objectives Many multidrug-resistant Gram-negative bacilli (MDR-GNB) harbour
multiple β-lactamases. The aim of this study was to assess the impact of multiple β-
lactamase carriage on the accuracy of susceptibility tests and extended-spectrum β-
lactamase (ESBL) and carbapenemase confirmation methods. Methods A total of 50 MDR-
GNB, of which 29 carried multiple β-lactamases, underwent broth microdilution (BMD) and
disk diffusion (DD) testing as well as confirmation tests for ESBLs and carbapenemases …
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